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Reality versus extrapolation: an academic perspectiveof cancer risk regulation. The health of the myocardium depends onits blood supply. There are three types that are stimulatedby different stimuli: mechanosensitive nociceptors (of A-delta?bers), sensitive to intense mechanical stimulation (e.g., plierspinching skin); temperature-sensitive (thermosensitive) noci-ceptors (of A-delta ?bers), sensitive to intense heat and cold;and polymodal nociceptors (of C ?bers), sensitive to noxiousstimuli of mechanical, thermal, or chemical nature (Patestas& Gartner, 2006). Can the relationship be described and quantified in a simple way?2.

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